Network Modeling Reveals Steps in Angiotensin Peptide Processing

Network modeling reveals steps in angiotensin peptide processing.

New insights into the intrarenal renin-angiotensin (Ang) system have modified our traditional view of the system. However, many finer details of this network of peptides and associated peptidases remain unclear. We hypothesized that a computational systems biology approach, applied to peptidomic data, could help to unravel the network of enzymatic conversions. We built and refined a Bayesian ne...

Steps toward peptide polymerization in polyacrylamide gels

Modeling In-Network Processing and Aggregation in Sensor Networks

The rapid advances in processor, memory and radio technology have enabled the development of distributed networks of sensor nodes capable of sensing and communicating using wireless media. The basic operation in sensor networks is the systematic gathering and transmission of sensed data to the end-user. The severe energy constraints and limited computing capabilities of the sensors present majo...

Network analysis reveals increased integration during emotional and motivational processing.

In recent years, a large number of human studies have investigated large-scale network properties of the brain, typically during the resting state. A critical gap in the knowledge base concerns the understanding of network properties of a focused set of brain regions during task conditions engaging these regions. Although emotion and motivation recruit many brain regions, it is currently unknow...

Web Service Discovery Processing Steps

The most straightforward but also most inflexible configuration approach for invocation of remote services is to hard wire the location, interface, behavior and other properties of remote services into the local application. Loosely coupled decentralized systems call for solutions that are more flexible and can seamlessly adapt to changing conditions. While advances have recently been made in t...